How to Generate the Best Chemotherapy Drug
Thursday, March 11th, 2010As a disease cancer consists of the uncontrolled malignant cellular growth, the invasion of organs and the metastasis. It seams that the cause of the condition is a combination of genetic predisposition and the exposure to some environmental toxins. Basically, the principle that makes a chemotherapy drug functional is the impairment of the cellular division of tissues with a fast growth rate. The fact that these drugs destroy cells leads to their being named cytotoxic.
In broad general terms, chemotherapy kills cells by means of chemical substances. In more particular terms, chemotherapy aims at destroying cancer and invasive micro-organisms that remain unaffected to other forms of treatment. Chemotherapy usually refers to antineoplastic drugs which are used to treat cancer or to the combination of these drugs into a cytotoxic standardized treatment regimen. From a non-oncological perspective, the term chemotherapy also refers to antibiotics – this is known as antibacterial chemotherapy.
A chemotherapy drug, or better a combination of such drugs, functions by destroying cells that divide quickly. Unfortunately, these drugs cannot make a selection between normal fast-dividing body cells and cancer cells. These other cells that get attacked by a chemotherapy drug are digestive tract linings, the bone marrow and the hair follicles. Thus, the main side effects of chemotherapy will include hair loss, the inflammation of the digestive tract and the reduced production of blood cells.
Among the other uses of the chemotherapy drug and cytostatic chemotherapy agents there are the treatment of autoimmune diseases (multiple sclerosis, rheumatoid arthritis) and the suppression of transplant rejections. More modern cancer treatments known as targeted therapy use anti-cancer medication that attacks only the abnormal proteins in cancer cells.
Different classes of chemotherapy drug medication are available at present. Thus there are antimetabolites, alkylating agents, topoisomerase inhibitors, anthracyclines and several others. Some newer agents, like monoclonal antibodies and tyrosine kinase inhibitors, do not interfere directly with the DNA as do the above mentioned ones.
These ones target a molecular abnormality in particular types of cancer such as chronic myelogenous leukemia or gastrointestinal stromal tumors. More special chemotherapy drug options only change the behavior of the tumor cells without affecting other tissues. Within these adjuvant therapies the option very commonly used is the hormone treatment. The decision to administer only one chemotherapy drug or a combination of several medicines belongs to the doctor and it is taken depending on the stage of the disease and the purpose of the treatment.
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